imp_region im_param not accepting all listed parameters

Question

Hello everyone,

I am trying to modify a list of parameters for the ToRORd_dynCl ionic model using imp_region[0].im_param defined in the parameter file. For some reason it is only accepting a certain length of the string of parameters mentioned. So for example in the im_param I define a long string for ionic model parameters but only the first say 100 characters of the string are being accepted. The characters in string after that throw an error saying "Unrecognized keyword". 

This is what I am defining in the parameter file:

num_imp_regions = 1

imp_region[0].im = ToRORd_dynCl

imp_region[0].num_IDs  = 65

imp_region[0].im_param = "flags=EPI,GNa=1.5788e+01,GNaL_b=1.8332e-01,Gto_b=8.1327e-02,PCa_b=2.5652e-04,GKr_b=6.2616e-02,GKs_b=1.1041e-03,GK1_b=1.4432e+00,Gncx_b=7.5696e-03,Pnak_b=5.0441e+01,GKb_b=6.6005e-02,GClCa=5.5524e-01,cmdnmax_b=1.8078e-01,Jup_b=1.1585e+00,Jrel_b=1.8615e+00"

This is the error I get when I run the simulation:

*** Unrecognized keyword 85e+00

*** Error reading parameters

The 85e+00 is a part of the value defined for Jup_b. 

I have tried assigning parameter modifications in multiple lines but in that case only the parameters defined in the last line are being modified. Does anyone know the reason for this error? Is it a bug? I am using CARPentry.

I would appreciate it if you could give me some advice on how to solve the problem!

Thanks

Answer 1

The parameter file seams to have a line limit for 255 characters.

As a quick fix you might try to rewrite your parameters to fit within that limit (removing +e00 or replacing -e02 with -e2 etc.). In your case it would result to a line:

imp_region[0].im_param="flags=EPI,GNa=15.788,GNaL_b=1.8332e-1,Gto_b=8.1327e-2,PCa_b=2.5652e-4,GKr_b=6.2616e-2,GKs_b=1.1041e-3,GK1_b=1.4432,Gncx_b=7.5696e-3,Pnak_b=5.0441e+1,GKb_b=6.6005e-2,GClCa=5.5524e-1,cmdnmax_b=1.8078e-1,Jup_b=1.1585,Jrel_b=1.8615"

For a more robust solution you would need to change the code of the simulator directly.