Community experiments

This is an idealized 2D cardiac infarct model designed with the purpose of replicating the setup used in our study entitled "An automated near-real time computational method for induction and treatment of scar-related ventricular tachycardias" (accepted) Medical Image Analysis (2022).

In silico experiments to study the sinoatrial node characteristics. The experiment script is able to modify several electrophysiological parameters using as an input a vtk file.

Single cell simulations of KCNQ1 mutants using human myocyte models. Use external/runAll.py to launch all simulations.

This experiment simulates the extended sinoatrial node cell models of Severi et al. (2012) and Fabbri et al. (2017) with several [Ca2+]o and [ISO]. The extension of the AC-cAMP-PKA signalling cascade is based on the work of Behar et al. (2016).

This is an example to run the PEERP (Pacing at the End of the Refractory Period, Luca Azzolin et al., https://doi.org/10.3389/fphys.2021.656411) protocol using a monoatrial left atrium (LA) mesh, with fibers and region annotation. The mesh is the mean LA geometry from the SSM (Statistical Shape Model) proposed by Claudia Nagel et al. ([doi:10.5281/zenodo.4309957](https://doi.org/10.5281/zenodo.4309957)) and the fibers and annotations were generated using AugmentA code https://github.com/KIT-IBT/AugmentA (https://doi.org/10.1016/j.compmedimag.2023.102265) by Luca Azzolin et al.